The prostate is a golf ball-sized gland located under the bladder and in front of the rectum in men. While all of its functions are not known, the prostate adds fluid and nutrients to sperm to produce semen and allow the sperm to move more effectively. An enlarged prostate, also known as benign prostatic hyperplasia (BPH), is a common condition that occurs as men age. BPH causes the prostate to press against the urethra which results in urinary problems. It is believed that an enlarged prostate may be due to an excess of certain hormones in the body.
Symptoms of an Enlarged Prostate
As men mature, the prostate goes through two main growth phases, first during puberty and again around the age of 25. This second growth phase may continue for many years, and can eventually lead to an enlarged prostate later in life. In fact, more than 50 percent of men aged 50 and older are affected by this condition. As the prostate expands, more and more urinary problems develop. Men with an enlarged prostate may experience:
- Difficulty starting to urinate
- Inability to completely empty the bladder
- Slowed urine stream
- Frequent urination
- Sudden urge to urinate
As symptoms progress, patients may also develop bladder stones, blood in the urine or a bladder infection. This condition will continue to worsen if left untreated.
Diagnosis of an Enlarged Prostate
An enlarged prostate is diagnosed after a thorough physical examination by a doctor, which may also include the following additional tests:
- Digital rectal exam
- Prostate specific antigen test or PSA
A series of urodynamic tests may also be performed to evaluate the function of the bladder and the urinary tract.
Non-Surgical Treatment of an Enlarged Prostate
Treatment for an enlarged prostate may vary depending on the severity of the condition. Patients with mild symptoms may only need to monitor their condition for signs that it is worsening, while more severe cases may require medication to inhibit hormone production or relax the muscle in the prostate. Two common types of medication for an enlarged prostate include:
Alpha blockers relax the muscles in the bladder and prostate. They can help improve urine flow and reduce risk of bladder obstruction. They are often prescribed to men with smaller prostates.
5-Alpha Reductase Inhibitors
5-alpha reductase inhibitors block the male hormone that stimulates the prostate. These drugs are generally prescribed to men with significantly enlarged prostates. In addition to relieving symptoms, 5-alpha reductase inhibitors increase urinary flow and may even help shrink the prostate.
In some cases, a combination of both medications has proven to be effective in slowing the progression of the disease and alleviating symptoms.
Surgical Treatment of an Enlarged Prostate
In some cases, surgery may be required to remove the prostate tissue that is blocking the flow of urine. There are several different surgical procedures available for treating an enlarged prostate, including:
Transurethral resection of the prostate, or TURP, is a surgery used to treat an enlarged prostate with no external incisions. A resectoscope is inserted through the urethra, and tissue is cut away from the enlarged prostate.
Transurethral Needle Ablation
With transurethral needle ablation, or TUNA, needles are inserted in the prostate and emit low-level frequency radio waves that create a heat that destroys the prostate tissue. The TUNA procedure utilizes high-frequency radio waves to destroy the superfluous tissue of the prostate gland. Needles are inserted into the enlarged areas of the prostate gland and send high-frequency radio waves, which will destroy the tissue around the needles. This reduces pressure on the urethra, and therefore decrease urinary difficulties.
Transurethral Microwave Thermotherapy
Transurethral microwave thermotherapy, also known as TUMT, uses high-frequency radio waves to cause injury to the prostate and provides relief for bladder obstruction. The surgeon utilizes a special catheter, called an antenna, that is inserted through the urethra to a location inside the prostate. Microwave energy is then used to heat the inside of the prostate while cooling fluid is circulated around the microwave antenna to prevent heat from damaging the wall of the urethra. As the damaged prostate tissue heals, it shrinks significantly, reducing the blockage of urine flow.
Transurethral Vaporization of the Prostate
During transurethral vaporization of the prostate, also known as TUVP, an elecrode transmits a current that vaporizes prostate tissue. Using an instrument that delivers high-voltage electrical current, the doctor pinpoints the prostrate tissue that will be destroyed.
In the case of a significantly enlarged prostate, open surgery is usually recommended. An incision is made in the lower abdomen and the interior of the prostate is removed, leaving the outer lining of compressed normal prostate tissue. This surgery results in the greatest increase in urinary flow of all treatment techniques.
Surgery for an enlarged prostate usually provides effective results for at least 15 years. Patients should continue to have rectal and prostate exams once a year and should see their doctor at the first sign of recurring symptoms.
There are a wide range of treatment options available for an enlarged prostrate and if treated promptly and effectively, patients can live relatively normal lives.
- National Institutes of Health
- Centers for Disease Control and Prevention
- Eunice Kennedy Shriver National Institute of Child Health and Human Development
- U.S. Department of Health & Human Services
- U.S. National Library of Medicine
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